The rocky road to personalized medicine: computational and statistical challenges
نویسندگان
چکیده
109 ISSN 1741-0541 10.2217/PME.12.1 © 2012 Future Medicine Ltd Personalized Medicine (2012) 9(2), 109–114 “On the road towards in silico humans with in silico diseases that are applicable to treatment prediction in personalized medicine, it is necessary to consider the intermediate steps where statistical models are built for the purposes of both prediction and systems level understanding, from the current and emerging data.”
منابع مشابه
Personalized medicine approach in dental management, abilities and challenges: A Review Article
Background and Aims: Advances of genetic science in genomic techniques have led introducing new diagnostic systems to study the diseases or treatment efficacies. In this science, which named “Personalized Medicine”, human genetic structure is used for evaluation of the diagnosis, treatment, and prevention of disease. Regarding the limited number of studies regarding this issue in Oral & Maxillo...
متن کاملRole of personalized medicine in cardiovascular disease: A narrative review
Cardiovascular diseases are the leading cause of mortality each year. Both environmental and genetic risk factors significantly influence the incidence and progression of these diseases. In recent decades, with the development of genetics and genome-determining tools, different genes have been found associated with numerous diseases. Determining these genes helps us to suggest a more effective ...
متن کاملCritical Challenges for Adopting Personalized Medicine System in Healthcare Management: Perspectives of Clinicians and Patients
Personalized Medicine is an emerging approach in today’s healthcare management. It bears a very strong potential to consolidate modern e-health systems fundamentally. Scientists have already discovered some of the personalized drugs that can shift the whole medicare process into a new dimension. However, bringing the change in healthcare management is an easy task. There are several critical ch...
متن کاملCROSSING THE WAY OF PRECISION MEDICINE APPROACH IN PERSONALIZED MEDICINE RESEARCH CENTER: A SYSTEMATIC REVIEW
Background: Precision medicine is a new approach in the field of medical sciences that utilizes the genetic characteristics of each patient along with clinical information to guide decisions related to diagnosis and early treatment of diseases. The Personalized Medicine Research Center, as the only center approved by the Ministry of Health, is working on precision medicine context and producing...
متن کاملPersonalized Immunology in Cancer: Paving the Way Towards a Better Quality of Life
Conventionally, in specific diseases, patients receive similar therapies; relying on a "one size fits all" approach. The discovery of P5 (Predictive, Preventive, Personalized, Participatory, and psycho-cognitive) improves personalized diagnosis, treatment, and prognosis. Considering the high prevalence, mortality rate, and complexity of cancers, there is a critical necessity to choose specific ...
متن کامل